Standard

Fluid intelligence

SFMBT1 · rs62253605

Where this position leads

Condition: Intelligence

rs62253605 Condition: Intelligence Intelligence Condition rs62253605 rs62253605 SFMBT1

What the study found

Who was studied 182,798 British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0243 lower; p = 2 × 10−12.

How common The C allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 3, band 3p21.1 — in an intron of SFMBT1.

What each result means

C/C Two copies of the version the research linked to Fluid intelligence. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Fluid intelligence. That is a smaller link than two copies.
T/T No copy of the version the research linked to Fluid intelligence. This is the starting point the study compared everyone against.
Source

Questions about rs62253605

What is rs62253605?

rs62253605 is a single position in the genome, in or near the SFMBT1 gene. Published research associates it with fluid intelligence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62253605 linked to?

On MyGeneLog this position is linked to Intelligence. The research behind each link, and its sources, are set out on that condition page.

Does having rs62253605 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62253605 come from?

GWAS Catalog, Communications biology 2026, PMID:42092107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Fluid intelligence (rs62253605). MyGeneLog™. https://www.mygenelog.com/variants/rs62253605

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