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Glaucoma

MIR4776-1 · rs62188040

Where this position leads

Condition: Glaucoma

rs62188040 Condition: Glaucoma Glaucoma Condition rs62188040 rs62188040 MIR4776-1

What the study found

Who was studied 7,947 British ancestry cases, 119,318 British ancestry controls.

The effect Each copy of the C allele carried 1.17 times the odds of Glaucoma; p = 3 × 10−8.

How common The C allele had a frequency of about 89% in the people studied.

Where it sits Chromosome 2, band 2q34 — between genes, 25.7 kb from PCED1CP.

What each result means

A/A No copy of the version the research linked to Glaucoma. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Glaucoma. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Glaucoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs62188040

What is rs62188040?

rs62188040 is a single position in the genome, in or near the MIR4776-1 gene. Published research associates it with glaucoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62188040 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs62188040 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62188040 come from?

GWAS Catalog, Nat Genet 2020, PMID:31959993. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glaucoma (rs62188040). MyGeneLog™. https://www.mygenelog.com/variants/rs62188040

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