Sensitive

Meniere's disease

near XRCC6P1 · rs61861121

Where this position leads

Condition: Meniere's Disease

rs61861121 Condition: Meniere's Disease Meniere's Disease Condition rs61861121 rs61861121 near XRCC6P1

What the study found

Who was studied 7,303 European ancestry cases, 1,564,233 European ancestry controls, 1,301 East Asian ancestry cases, 187,114 East Asian ancestry controls, 296 Hispanic or Latin American cases, 129,993 Hispanic or Latin American controls, 69 cases, 81,202 controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−12.

How common The A allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 10, band 10q23.33 — between genes, 15.5 kb from XRCC6P1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Meniere's disease compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Meniere's disease.
G/G Published research associates this genotype with typical/baseline likelihood of Meniere's disease — no copies of the reported risk allele.
Source

Questions about rs61861121

What is rs61861121?

rs61861121 is a single position in the genome, in or near the near XRCC6P1 gene. Published research associates it with meniere's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61861121 linked to?

On MyGeneLog this position is linked to Meniere's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs61861121 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61861121 come from?

GWAS Catalog, American journal of human genetics 2026, PMID:42302782. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Meniere's disease (rs61861121). MyGeneLog™. https://www.mygenelog.com/variants/rs61861121

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