Sensitive

Type 2 diabetes

PDIK1L · rs61776592

Where this position leads

Condition: Type 2 Diabetes

rs61776592 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs61776592 rs61776592 PDIK1L

What the study found

Who was studied 51,256 African, African American, East Asian, South Asian, European, Middle Eastern, admixed American, other or other admixed ancestry cases, 370,487 African, African American, East Asian, South Asian, European, Middle Eastern, admixed American, other or other admixed ancestry controls; replicated in 73,088 African, African American, East Asian, South Asian, European, Middle Eastern, admixed American, other or other admixed ancestry cases, 79,827 African, African American, East Asian, South Asian, European, Middle Eastern, admixed American, other or other admixed ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0658 higher (95% confidence interval 0.046-0.086); p = 8 × 10−11.

How common The T allele had a frequency of about 82% in the people studied.

Where it sits Chromosome 1, band 1p36.11 — in an intron of PDIK1L.

What each result means

A/A No copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs61776592

What is rs61776592?

rs61776592 is a single position in the genome, in or near the PDIK1L gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61776592 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs61776592 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61776592 come from?

GWAS Catalog, Nature genetics 2024, PMID:39379762. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (rs61776592). MyGeneLog™. https://www.mygenelog.com/variants/rs61776592

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