Standard
Optic disc area
CARD10 · rs6000762
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Optic disc area compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Optic disc area.
T/T
Published research associates this genotype with typical/baseline likelihood of Optic disc area — no copies of the reported risk allele.
Source
Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area
Khor CC,
Ramdas WD,
Vithana EN,
Cornes BK,
Sim X,
Tay WT,
Saw SM,
Zheng Y,
Lavanya R,
Wu R,
Wang JJ,
Mitchell P
and 13 more — show all
Uitterlinden AG,
Rivadeneira F,
Teo YY,
Chia KS,
Seielstad M,
Hibberd M,
Vingerling JR,
Klaver CC,
Jansonius NM,
Tai ES,
Wong TY,
van Duijn CM,
Aung T
Human molecular genetics · 2011 · PMID 21307088
Questions about rs6000762
What is rs6000762?
rs6000762 is a single position in the genome, in or near the CARD10 gene. Published research associates it with optic disc area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6000762 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6000762 come from?
GWAS Catalog, Hum Mol Genet 2011, PMID:21307088. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants