0 3111823214Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others14Total31Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 10,523 European ancestry cases, 203,579 European ancestry controls, 411 Hispanic cases, 4,778 Hispanic controls, 463 East Asian ancestry cases, 4,907 East Asian ancestry controls, 298 African American cases, 1,549 African American controls, 204 South Asian ancestry cases, 4,916 South Asian ancestry controls, 272 African British cases, 4,831 African British controls, 144 mixed ancestry cases, 3,427 mixed ancestry controls.
The effect
Each copy of the C allele carried 1.15 times the odds of Glaucoma (primary open-angle) (95% confidence interval 1.11-1.20); p = 1 × 10−13.
Where it sits Chromosome 22, band 22q11.21 — between genes, 1.8 kb from LOC124905080.
What each result means
C/CTwo copies of the version the research linked to Glaucoma (primary open-angle). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Glaucoma (primary open-angle). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Glaucoma (primary open-angle). This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 29891935 · open access
Questions about rs58714937
What is rs58714937?
rs58714937 is a single position in the genome, in or near the TXNRD2 gene. Published research associates it with glaucoma (primary open-angle). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs58714937 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs58714937 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs58714937 come from?
GWAS Catalog, Nat Commun 2018, PMID:29891935. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 3111823214Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others14Total31Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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