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X-17654 levels

SLCO1B1 · rs58487503

Where this position leads

Drugs: Statins, Ticagrelor

rs58487503 Drug: Statins Statins Drug Drug: Ticagrelor Ticagrelor Drug rs58487503 rs58487503 SLCO1B1

What the study found

Who was studied 8,809 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.208 higher (95% confidence interval 0.17-0.25); p = 3 × 10−24.

Where it sits Chromosome 12, band 12p12.1 — in an intron of SLCO1B1.

What each result means

A/A Two copies of the version the research linked to X-17654 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to X-17654 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to X-17654 levels. This is the starting point the study compared everyone against.
Source

Questions about rs58487503

What is rs58487503?

rs58487503 is a single position in the genome, in or near the SLCO1B1 gene. Published research associates it with x-17654 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs58487503 affect how medicines work?

SLCO1B1 carries pharmacogenomic findings for Statins, Ticagrelor. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs58487503 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs58487503 come from?

GWAS Catalog, Metabolites 2022, PMID:35050183. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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X-17654 levels (rs58487503). MyGeneLog™. https://www.mygenelog.com/variants/rs58487503

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