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Who was studied 215 African American or Afro-Caribbean cases, 121,633 African American or Afro-Caribbean controls, 975 European ancestry cases, 449,793 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 3.85 lower (95% confidence interval 3.83-3.86); p = 9 × 10−12.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 7, band 7q36.1 — in an intron of GALNTL5.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Hodgkin's disease (PheCode 201) — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hodgkin's disease (PheCode 201).
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hodgkin's disease (PheCode 201) compared to the general population.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs576160676
What is rs576160676?
rs576160676 is a single position in the genome, in or near the GALNTL5 gene. Published research associates it with hodgkin's disease (phecode 201). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs576160676 linked to?
On MyGeneLog this position is linked to Hodgkin's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs576160676 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs576160676 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon0Apple0Others0Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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