Standard

Dyshidrosis (PheCode 705.1)

DLG2 · rs571769378

Where this position leads

Condition: Dyshidrosis

rs571769378 Condition: Dyshidrosis Dyshidrosis Condition rs571769378 rs571769378 DLG2

What the study found

Who was studied 633 African American or Afro-Caribbean cases, 120,286 African American or Afro-Caribbean controls, 1,549 European ancestry cases, 446,736 European ancestry controls, 273 Hispanic or Latin American cases, 59,198 Hispanic or Latin American controls.

The effect Each copy of the C allele shifted the measure 3.08 lower (95% confidence interval 3.05-3.1); p = 2 × 10−11.

How common The C allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 11, band 11q14.1 — in an intron of DLG2.

What each result means

C/C Two copies of the version the research linked to Dyshidrosis (PheCode 705.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Dyshidrosis (PheCode 705.1). That is a smaller link than two copies.
T/T No copy of the version the research linked to Dyshidrosis (PheCode 705.1). This is the starting point the study compared everyone against.
Source

Questions about rs571769378

What is rs571769378?

rs571769378 is a single position in the genome, in or near the DLG2 gene. Published research associates it with dyshidrosis (phecode 705.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs571769378 linked to?

On MyGeneLog this position is linked to Dyshidrosis. The research behind each link, and its sources, are set out on that condition page.

Does having rs571769378 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs571769378 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Dyshidrosis (PheCode 705.1) (rs571769378). MyGeneLog™. https://www.mygenelog.com/variants/rs571769378

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