Gene Knowledge Graph
UTC
Sensitive

Systemic lupus erythematosus

IL12A · rs564799

Where this position leads

Condition: Systemic Lupus Erythematosus

rs564799 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs564799 rs564799 IL12A

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Systemic lupus erythematosus compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Systemic lupus erythematosus.
T/T Published research associates this genotype with typical/baseline likelihood of Systemic lupus erythematosus — no copies of the reported risk allele.
Source
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
Bentham J, Morris DL, Graham DSC, Pinder CL, Tombleson P, Behrens TW, Martín J, Fairfax BP, Knight JC, Chen L, Replogle J, Syvänen AC
and 6 more — show all
Rönnblom L, Graham RR, Wither JE, Rioux JD, Alarcón-Riquelme ME, Vyse TJ
Nature genetics · 2015 · PMID 26502338 · open access

What people read about alongside this

Heart and circulation1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs564799

What is rs564799?

rs564799 is a single position in the genome, in or near the IL12A gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs564799 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs564799?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs564799 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs564799 come from?

GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants