Sensitive

Systemic lupus erythematosus

IL12A · rs564799

Where this position leads

Condition: Systemic Lupus Erythematosus

rs564799 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs564799 rs564799 IL12A

What the study found

Who was studied 5,201 European ancestry cases, 9,066 European ancestry controls; replicated in 2,018 European ancestry cases, 6,925 European ancestry controls.

The effect Each copy of the C allele carried 1.14 times the odds of Systemic lupus erythematosus (95% confidence interval 1.09–1.18); p = 2 × 10−9.

Where it sits Chromosome 3, band 3q25.33 — in an intron of IL12A-AS1.

What each result means

C/C Two copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
T/T No copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs564799

What is rs564799?

rs564799 is a single position in the genome, in or near the IL12A gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs564799 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs564799?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs564799 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs564799 come from?

GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systemic lupus erythematosus (rs564799). MyGeneLog™. https://www.mygenelog.com/variants/rs564799

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