0 24111712326Reads by AI crawlersClaude1ChatGPT0Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 20,373 European ancestry individuals, 2,131 Erasmus Rucphen (founder/genetic isolate) individuals; replicated in 7,302 Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.047 higher (95% confidence interval 0.035-0.059); p = 4 × 10−17.
Where it sits Chromosome 22, band 22q13.1 — in an intron of CARD10.
What each result means
A/ATwo copies of the version the research linked to Optic disc area. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Optic disc area. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Optic disc area. This is the starting point the study compared everyone against.
rs56385951 is a single position in the genome, in or near the CARD10 gene. Published research associates it with optic disc area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs56385951 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs56385951 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs56385951 come from?
GWAS Catalog, Hum Mol Genet 2017, PMID:28073927. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 24111712326Reads by AI crawlersClaude1ChatGPT0Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Optic disc area (rs56385951). MyGeneLog™. https://www.mygenelog.com/variants/rs56385951