Sensitive

Coronary artery disease

CETP · rs56228609

Where this position leads

Condition: Coronary Artery Disease

Drug: Statins

rs56228609 Condition: Coronary Artery Disease Coronary Artery Disease Condition Drug: Statins Statins Drug rs56228609 rs56228609 CETP

What the study found

Who was studied 34,541 cases, 261,984 controls; replicated in 88,192 cases, 162,544 controls.

The effect Each copy of the T allele shifted the measure 0.039 lower (95% confidence interval 0.025-0.053); p = 3 × 10−8.

How common The T allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 16, band 16q13 — between genes, 7.3 kb from LOC124903811.

What each result means

C/C No copy of the version the research linked to Coronary artery disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Coronary artery disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs56228609

What is rs56228609?

rs56228609 is a single position in the genome, in or near the CETP gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs56228609 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does rs56228609 affect how medicines work?

CETP carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs56228609 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56228609 come from?

GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary artery disease (rs56228609). MyGeneLog™. https://www.mygenelog.com/variants/rs56228609

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