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Who was studied 373,733 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 6.59 z score lower; p = 4 × 10−11.
How common The T allele had a frequency of about 44% in the people studied.
Where it sits Chromosome 16, band 16q24.2 — in an intron of FBXO31.
What each result means
G/GNo copy of the version the research linked to Experiencing mood swings. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Experiencing mood swings. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Experiencing mood swings. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 29500382 · open access
Questions about rs56059702
What is rs56059702?
rs56059702 is a single position in the genome, in or near the FBXO31 gene. Published research associates it with experiencing mood swings. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs56059702 linked to?
On MyGeneLog this position is linked to Irritable Mood. The research behind each link, and its sources, are set out on that condition page.
Does having rs56059702 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs56059702 come from?
GWAS Catalog, Nature communications 2018, PMID:29500382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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