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Who was studied 633 African American or Afro-Caribbean cases, 120,286 African American or Afro-Caribbean controls, 1,549 European ancestry cases, 446,736 European ancestry controls, 273 Hispanic or Latin American cases, 59,198 Hispanic or Latin American controls.
The effect
Each copy of the G allele shifted the measure 2.63 lower (95% confidence interval 2.59-2.67); p = 6 × 10−12.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 10, band 10q26.3 — in an intron of TCERG1L.
What each result means
A/ANo copy of the version the research linked to Dyshidrosis (PheCode 705.1). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Dyshidrosis (PheCode 705.1). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Dyshidrosis (PheCode 705.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs558850072
What is rs558850072?
rs558850072 is a single position in the genome, in or near the TCERG1L gene. Published research associates it with dyshidrosis (phecode 705.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs558850072 linked to?
On MyGeneLog this position is linked to Dyshidrosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs558850072 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs558850072 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 725Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others5Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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