0 913113Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot1Amazon1Apple0Others3Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 276 African American or Afro-Caribbean cases, 121,333 African American or Afro-Caribbean controls, 769 European ancestry cases, 449,707 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 2.32 lower (95% confidence interval 2.28-2.37); p = 8 × 10−13.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 4, band 4p15.33 — between genes, 128.4 kb from HS3ST1.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Acute pericarditis (PheCode 420.21) — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Acute pericarditis (PheCode 420.21).
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Acute pericarditis (PheCode 420.21) compared to the general population.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs556330122
What is rs556330122?
rs556330122 is a single position in the genome, in or near the near HS3ST1 gene. Published research associates it with acute pericarditis (phecode 420.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs556330122 linked to?
On MyGeneLog this position is linked to Acute Pericarditis. The research behind each link, and its sources, are set out on that condition page.
Does having rs556330122 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs556330122 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 913113Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot1Amazon1Apple0Others3Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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