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Thyroiditis (PheCode 245)

near RNA5SP293 · rs549207705

Where this position leads

Condition: Thyroiditis

rs549207705 Condition: Thyroiditis Thyroiditis Condition rs549207705 rs549207705 near RNA5SP2…

What the study found

Who was studied 392 African American or Afro-Caribbean cases, 121,065 African American or Afro-Caribbean controls, 1,904 European ancestry cases, 447,836 European ancestry controls, 226 Hispanic or Latin American cases, 59,493 Hispanic or Latin American controls.

The effect Each copy of the C allele shifted the measure 1.53 lower (95% confidence interval 1.46-1.61); p = 2 × 10−12.

How common The C allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 9, band 9q31.2 — between genes, 18.2 kb from RNA5SP293.

What each result means

C/C Two copies of the version the research linked to Thyroiditis (PheCode 245). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Thyroiditis (PheCode 245). That is a smaller link than two copies.
G/G No copy of the version the research linked to Thyroiditis (PheCode 245). This is the starting point the study compared everyone against.
Source

Questions about rs549207705

What is rs549207705?

rs549207705 is a single position in the genome, in or near the near RNA5SP293 gene. Published research associates it with thyroiditis (phecode 245). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs549207705 linked to?

On MyGeneLog this position is linked to Thyroiditis. The research behind each link, and its sources, are set out on that condition page.

Does having rs549207705 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs549207705 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Thyroiditis (PheCode 245) (rs549207705). MyGeneLog™. https://www.mygenelog.com/variants/rs549207705

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