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Who was studied 775 African American or Afro-Caribbean cases, 120,581 African American or Afro-Caribbean controls, 1,216 European ancestry cases, 449,020 European ancestry controls, 213 Hispanic or Latin American cases, 59,533 Hispanic or Latin American controls.
The effect
Each copy of the T allele shifted the measure 3.88 lower (95% confidence interval 3.87-3.9); p = 3 × 10−11.
How common The T allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 12, band 12q21.32 — between genes, 42.8 kb from RPS4XP15.
What each result means
A/ANo copy of the version the research linked to Glomerulonephritis (PheCode 580.1). This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Glomerulonephritis (PheCode 580.1). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Glomerulonephritis (PheCode 580.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs549120028
What is rs549120028?
rs549120028 is a single position in the genome, in or near the near RPS4XP15 gene. Published research associates it with glomerulonephritis (phecode 580.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs549120028 linked to?
On MyGeneLog this position is linked to Glomerulonephritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs549120028 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs549120028 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 71123Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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