0 8233Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others3Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 285 African American or Afro-Caribbean cases, 121,215 African American or Afro-Caribbean controls, 660 European ancestry cases, 449,307 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 3.81 lower (95% confidence interval 3.79-3.82); p = 4 × 10−17.
How common The A allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 15, band 15q26.3 — in an intron of CERS3.
What each result means
A/ATwo copies of the version the research linked to Progressive myopia (PheCode 360.2). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Progressive myopia (PheCode 360.2). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Progressive myopia (PheCode 360.2). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs547989689
What is rs547989689?
rs547989689 is a single position in the genome, in or near the CERS3 gene. Published research associates it with progressive myopia (phecode 360.2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs547989689 linked to?
On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.
Does having rs547989689 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs547989689 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 8233Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others3Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.