Sensitive

Meniere's disease

BRMS1L · rs529699157

Where this position leads

Condition: Meniere's Disease

rs529699157 Condition: Meniere's Disease Meniere's Disease Condition rs529699157 rs529699157 BRMS1L

What the study found

Who was studied 1,290 East Asian ancestry cases, 177,436 East Asian ancestry controls.

The effect Each copy of the T allele shifted the measure 2.96 higher (95% confidence interval 1.93-4); p = 2 × 10−8.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 14, band 14q13.2 — in an intron of BRMS1L.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Meniere's disease — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Meniere's disease.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Meniere's disease compared to the general population.
Source

Questions about rs529699157

What is rs529699157?

rs529699157 is a single position in the genome, in or near the BRMS1L gene. Published research associates it with meniere's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs529699157 linked to?

On MyGeneLog this position is linked to Meniere's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs529699157 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs529699157 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Meniere's disease (rs529699157). MyGeneLog™. https://www.mygenelog.com/variants/rs529699157

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