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Who was studied 314 African American or Afro-Caribbean cases, 120,045 African American or Afro-Caribbean controls, 588 European ancestry cases, 447,585 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 3.86 lower (95% confidence interval 3.84-3.87); p = 3 × 10−13.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 2, band 2p14 — in an intron of LINC01828.
What each result means
G/GTwo copies of the version the research linked to Costochondritis (PheCode 733.6). That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Costochondritis (PheCode 733.6). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Costochondritis (PheCode 733.6). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs528594155
What is rs528594155?
rs528594155 is a single position in the genome, in or near the LINC01828 gene. Published research associates it with costochondritis (phecode 733.6). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs528594155 linked to?
On MyGeneLog this position is linked to Costochondritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs528594155 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs528594155 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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