Standard

Subjective well-being (MTAG)

RERE · rs4908768

Where this position leads

Condition: Depression (Self-Reported Symptoms)

rs4908768 Condition: Depression (Self-Reported Symptoms) Depression (Self-Reported Symptoms) Condition rs4908768 rs4908768 RERE

What the study found

Who was studied 388,538 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0135 higher (95% confidence interval 0.009-0.018); p = 6 × 10−9.

How common The G allele had a frequency of about 80% in the people studied.

Where it sits Chromosome 1, band 1p36.23 — in an intron of RERE.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Subjective well-being (MTAG) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Subjective well-being (MTAG).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Subjective well-being (MTAG) compared to the general population.
Source

Questions about rs4908768

What is rs4908768?

rs4908768 is a single position in the genome, in or near the RERE gene. Published research associates it with subjective well-being (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4908768 linked to?

On MyGeneLog this position is linked to Depression (Self-Reported Symptoms). The research behind each link, and its sources, are set out on that condition page.

Does having rs4908768 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4908768 come from?

GWAS Catalog, Nat Genet 2018, PMID:29292387. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Subjective well-being (MTAG) (rs4908768). MyGeneLog™. https://www.mygenelog.com/variants/rs4908768

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