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Menarche (age at onset)

MCHR2 · rs4840086

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Menarche (age at onset) — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2010, PMID:21102462)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Menarche (age at onset). (GWAS Catalog, Nat Genet 2010, PMID:21102462)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Menarche (age at onset) compared to the general population. (GWAS Catalog, Nat Genet 2010, PMID:21102462)

Source: GWAS Catalog, Nat Genet 2010, PMID:21102462

Questions about rs4840086

What is rs4840086?

rs4840086 is a single position in the genome, in or near the MCHR2 gene. Published research associates it with menarche (age at onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4840086 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4840086 come from?

GWAS Catalog, Nat Genet 2010, PMID:21102462. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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