G/GPublished research associates this genotype with typical/baseline likelihood of Schizophrenia — no copies of the reported risk allele. (GWAS Catalog, Nature 2014, PMID:25056061)
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Schizophrenia. (GWAS Catalog, Nature 2014, PMID:25056061)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Schizophrenia compared to the general population. (GWAS Catalog, Nature 2014, PMID:25056061)
Source: GWAS Catalog, Nature 2014, PMID:25056061
Questions about rs4523957
What is rs4523957?
rs4523957 is a single position in the genome, in or near the SGSM2 gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4523957 linked to?
On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.
Does having rs4523957 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4523957 come from?
GWAS Catalog, Nature 2014, PMID:25056061. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.