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White blood cell count

CDK6 · rs445

Where this position leads

Condition: Blood Cell Counts

rs445 Condition: Blood Cell Counts Blood Cell Counts Condition rs445 rs445 CDK6

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of White blood cell count — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with White blood cell count.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of White blood cell count compared to the general population.
Source
Genome-wide association study of hematological and biochemical traits in a Japanese population
Kamatani Y, Matsuda K, Okada Y, Kubo M, Hosono N, Daigo Y, Nakamura Y, Kamatani N
Nature genetics · 2010 · PMID 20139978

What people read about alongside this

Depression and stress1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs445

What is rs445?

rs445 is a single position in the genome, in or near the CDK6 gene. Published research associates it with white blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs445 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs445?

Subjects that appear in the title or abstract of the same papers as this rsID include depression and stress (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs445 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs445 come from?

GWAS Catalog, Nat Genet 2010, PMID:20139978. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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