3 43123723124Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity3Meta AI7Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,902 European ancestry cases, 1,929 European ancestry controls; replicated in 18,284 European ancestry cases, 18,926 European ancestry controls.
The effect
Each copy of the C allele carried 1.11 times the odds of Colorectal cancer (95% confidence interval 1.08-1.15); p = 8 × 10−10.
How common The C allele had a frequency of about 46% in the people studied.
Where it sits Chromosome 14, band 14q22.2 — between genes, 4.2 kb from MIR5580.
What each result means
C/CTwo copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
rs4444235 is a single position in the genome, in or near the BMP4 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4444235 linked to?
On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs4444235 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4444235 come from?
GWAS Catalog, Nat Genet 2008, PMID:19011631. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 43123723124Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity3Meta AI7Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Colorectal cancer (rs4444235). MyGeneLog™. https://www.mygenelog.com/variants/rs4444235