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Feeling miserable

NCAM1 · rs4424705

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Feeling miserable compared to the general population. (GWAS Catalog, Nat Commun 2018, PMID:29500382)
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Feeling miserable. (GWAS Catalog, Nat Commun 2018, PMID:29500382)
T/T Published research associates this genotype with typical/baseline likelihood of Feeling miserable — no copies of the reported risk allele. (GWAS Catalog, Nat Commun 2018, PMID:29500382)

Source: GWAS Catalog, Nat Commun 2018, PMID:29500382

Questions about rs4424705

What is rs4424705?

rs4424705 is a single position in the genome, in or near the NCAM1 gene. Published research associates it with feeling miserable. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4424705 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4424705 come from?

GWAS Catalog, Nat Commun 2018, PMID:29500382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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