Standard

Systolic blood pressure

CYP17A1 · rs4409766

Where this position leads

Condition: Blood Pressure

rs4409766 Condition: Blood Pressure Blood Pressure Condition rs4409766 rs4409766 CYP17A1

What the study found

Who was studied 11,816 Han Chinese ancestry individuals; replicated in 69,146 Han Chinese ancestry individuals.

The effect Each copy of the T allele shifted the measure 1.24 higher (95% confidence interval 0.95-1.53); p = 6 × 10−17.

How common The T allele had a frequency of about 71% in the people studied.

Where it sits Chromosome 10, band 10q24.32 — in an intron of BORCS7.

What each result means

C/C No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs4409766

What is rs4409766?

rs4409766 is a single position in the genome, in or near the CYP17A1 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4409766 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs4409766?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs4409766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4409766 come from?

GWAS Catalog, Hum Mol Genet 2014, PMID:25249183. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systolic blood pressure (rs4409766). MyGeneLog™. https://www.mygenelog.com/variants/rs4409766

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