Sensitive

Type 2 diabetes

near DUSP9 · rs4391603

Where this position leads

Condition: Type 2 Diabetes

rs4391603 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs4391603 rs4391603 near DUSP9

What the study found

Who was studied 45,383 East Asian ancestry cases, 132,032 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.153 lower (95% confidence interval 0.14-0.17); p = 1 × 10−84.

How common The A allele had a frequency of about 33% in the people studied.

Where it sits Chromosome X, band Xq28 — between genes, 9.7 kb from DUSP9.

What each result means

A/A Two copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
G/G No copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
Source

Questions about rs4391603

What is rs4391603?

rs4391603 is a single position in the genome, in or near the near DUSP9 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4391603 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs4391603 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4391603 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (rs4391603). MyGeneLog™. https://www.mygenelog.com/variants/rs4391603

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