C/CPublished research associates this genotype with typical/baseline likelihood of Spherical equivalent or myopia (age of diagnosis) — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Spherical equivalent or myopia (age of diagnosis).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Spherical equivalent or myopia (age of diagnosis) compared to the general population.
Nature genetics · 2018 · PMID 29808027 · open access
Questions about rs4260345
What is rs4260345?
rs4260345 is a single position in the genome, in or near the THRB gene. Published research associates it with spherical equivalent or myopia (age of diagnosis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4260345 linked to?
On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.
Does having rs4260345 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4260345 come from?
GWAS Catalog, Nat Genet 2018, PMID:29808027. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.