2 503347123225Reads by AI crawlersClaude3ChatGPT3Google · Gemini0Perplexity4Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,820 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.209 lower; p = 3 × 10−22.
How common The A allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 12, band 12p12.1 — in an intron of SLCO1B1.
What each result means
A/ATwo copies of the version the research linked to Metabolic traits. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Metabolic traits. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Metabolic traits. This is the starting point the study compared everyone against.
rs4149081 is a single position in the genome, in or near the SLCO1B1 gene. Published research associates it with metabolic traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4149081 linked to?
On MyGeneLog this position is linked to Blood Metabolite Levels. The research behind each link, and its sources, are set out on that condition page.
Does rs4149081 affect how medicines work?
SLCO1B1 carries pharmacogenomic findings for Statins, Ticagrelor. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs4149081 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4149081 come from?
GWAS Catalog, Nature 2011, PMID:21886157. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 503347123225Reads by AI crawlersClaude3ChatGPT3Google · Gemini0Perplexity4Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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