Who was studied 269,867 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 6.35 z-score lower; p = 2 × 10−10.
Where it sits Chromosome 1, band 1p31.1 — a missense change in TTLL7.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Intelligence — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Intelligence.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Intelligence compared to the general population.
rs41293013 is a single position in the genome, in or near the TTLL7 gene. Published research associates it with intelligence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs41293013 linked to?
On MyGeneLog this position is linked to Intelligence. The research behind each link, and its sources, are set out on that condition page.
Does having rs41293013 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs41293013 come from?
GWAS Catalog, Nature genetics 2018, PMID:29942086. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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