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Intraocular pressure

TMEM212-AS1 · rs3850195

Where this position leads

Condition: Glaucoma

rs3850195 Condition: Glaucoma Glaucoma Condition rs3850195 rs3850195 TMEM212-AS1

What the study found

Who was studied 115,486 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.113 higher (95% confidence interval 0.082-0.145); p = 3 × 10−14.

How common The A allele had a frequency of about 75% in the people studied.

Where it sits Chromosome 3, band 3q26.31 — inside LOC105374218.

What each result means

A/A Two copies of the version the research linked to Intraocular pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Intraocular pressure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Intraocular pressure. This is the starting point the study compared everyone against.
Source

Questions about rs3850195

What is rs3850195?

rs3850195 is a single position in the genome, in or near the TMEM212-AS1 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3850195 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs3850195 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3850195 come from?

GWAS Catalog, Hum Mol Genet 2018, PMID:29617998. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Intraocular pressure (rs3850195). MyGeneLog™. https://www.mygenelog.com/variants/rs3850195

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