0 7133Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon3Apple0China (ByteDance, Huawei, Baidu…)0Others3Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 6,397 European, Hispanic or African American individuals; replicated in up to 2,466 African American individuals, up to 15,619 European ancestry individuals, 1,734 Hispanic ancestry children.
The effect
Each copy of the G allele shifted the measure 0.248 higher (95% confidence interval 0.19-0.31); p = 5 × 10−17.
How common The G allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 1, band 1p21.3 — in an intron of DPYD.
What each result means
A/ANo copy of the version the research linked to Metabolite levels (uracil; Uracil). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Metabolite levels (uracil; Uracil). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Metabolite levels (uracil; Uracil). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2023 · PMID 37253714 · open access
Questions about rs3790389
What is rs3790389?
rs3790389 is a single position in the genome, in or near the DPYD gene. Published research associates it with metabolite levels (uracil; uracil). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs3790389 affect how medicines work?
DPYD carries pharmacogenomic findings for Fluoropyrimidines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs3790389 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3790389 come from?
GWAS Catalog, Nature communications 2023, PMID:37253714. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 7133Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon3Apple0China (ByteDance, Huawei, Baidu…)0Others3Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.