Standard

Height

OPRM1 · rs3778150

Where this position leads

Condition: Height

Drug: Opioids

rs3778150 Condition: Height Height Condition Drug: Opioids Opioids Drug rs3778150 rs3778150 OPRM1

What the study found

Who was studied 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0076 higher (95% confidence interval 0.006-0.0092); p = 3 × 10−19.

How common The C allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 6, band 6q25.2 — in an intron of OPRM1.

What each result means

C/C Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Questions about rs3778150

What is rs3778150?

rs3778150 is a single position in the genome, in or near the OPRM1 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3778150 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does rs3778150 affect how medicines work?

OPRM1 carries pharmacogenomic findings for Opioids. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs3778150 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3778150 come from?

GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs3778150). MyGeneLog™. https://www.mygenelog.com/variants/rs3778150

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