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Tissue factor pathway inhibitor levels

F5 · rs3766104

Where this position leads

Drug: Combined hormonal contraceptives

rs3766104 Drug: Combined hormonal contraceptives Combined hormonal contraceptives Drug rs3766104 rs3766104 F5

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.518 lower (95% confidence interval 0.43-0.61); p = 4 × 10−29.

How common The A allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — in an intron of F5.

What each result means

A/A Two copies of the version the research linked to Tissue factor pathway inhibitor levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Tissue factor pathway inhibitor levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Tissue factor pathway inhibitor levels. This is the starting point the study compared everyone against.
Source

Questions about rs3766104

What is rs3766104?

rs3766104 is a single position in the genome, in or near the F5 gene. Published research associates it with tissue factor pathway inhibitor levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs3766104 affect how medicines work?

F5 carries pharmacogenomic findings for Combined hormonal contraceptives. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs3766104 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3766104 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Tissue factor pathway inhibitor levels (rs3766104). MyGeneLog™. https://www.mygenelog.com/variants/rs3766104

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