Standard

Fluid intelligence

near POM121L6P · rs375848868

Where this position leads

Condition: Intelligence

rs375848868 Condition: Intelligence Intelligence Condition rs375848868 rs375848868 near POM121L…

What the study found

Who was studied 182,798 British ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0372 higher; p = 4 × 10−14.

How common The G allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 6, band 6p22.2 — between genes, 4.1 kb from POM121L6P.

What each result means

G/G Two copies of the version the research linked to Fluid intelligence. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Fluid intelligence. That is a smaller link than two copies.
T/T No copy of the version the research linked to Fluid intelligence. This is the starting point the study compared everyone against.
Source

Questions about rs375848868

What is rs375848868?

rs375848868 is a single position in the genome, in or near the near POM121L6P gene. Published research associates it with fluid intelligence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs375848868 linked to?

On MyGeneLog this position is linked to Intelligence. The research behind each link, and its sources, are set out on that condition page.

Does having rs375848868 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs375848868 come from?

GWAS Catalog, Communications biology 2026, PMID:42092107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Fluid intelligence (rs375848868). MyGeneLog™. https://www.mygenelog.com/variants/rs375848868

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