Sensitive

Type 2 diabetes

FBRSL1 · rs3751297

Where this position leads

Condition: Type 2 Diabetes

rs3751297 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs3751297 rs3751297 FBRSL1

What the study found

Who was studied 38,841 European ancestry cases, 451,248 European ancestry controls, 45,383 East Asian ancestry cases, 132,032 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.052 higher (95% confidence interval 0.036-0.068); p = 1 × 10−10.

Where it sits Chromosome 12, band 12q24.33 — in the 3′ untranslated region of FBRSL1.

What each result means

A/A Two copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
G/G No copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
Source

Questions about rs3751297

What is rs3751297?

rs3751297 is a single position in the genome, in or near the FBRSL1 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3751297 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs3751297 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3751297 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (rs3751297). MyGeneLog™. https://www.mygenelog.com/variants/rs3751297

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