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Who was studied 286 African American or Afro-Caribbean cases, 121,446 African American or Afro-Caribbean controls, 19,217 European ancestry cases, 419,674 European ancestry controls, 429 Hispanic or Latin American cases, 59,212 Hispanic or Latin American controls.
The effect
Each copy of the C allele shifted the measure 3.22 lower (95% confidence interval 3.2-3.24); p = 3 × 10−11.
How common The C allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 12, band 12q23.1 — inside RMST.
What each result means
C/CTwo copies of the version the research linked to Squamous cell carcinoma (PheCode 172.22). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Squamous cell carcinoma (PheCode 172.22). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Squamous cell carcinoma (PheCode 172.22). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs369608544
What is rs369608544?
rs369608544 is a single position in the genome, in or near the RMST gene. Published research associates it with squamous cell carcinoma (phecode 172.22). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs369608544 linked to?
On MyGeneLog this position is linked to Squamous Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs369608544 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs369608544 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 4112Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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