Standard

Refractive error

near VSX2 · rs35797567

Where this position leads

Condition: Myopia

rs35797567 Condition: Myopia Myopia Condition rs35797567 rs35797567 near VSX2

What the study found

Who was studied 1,495,159 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0113 SD unit higher (95% confidence interval 0.0082-0.0144); p = 7 × 10−13.

How common The T allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 14, band 14q24.3 — between genes, 9.4 kb from VSX2.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Refractive error — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Refractive error.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Refractive error compared to the general population.
Source

Questions about rs35797567

What is rs35797567?

rs35797567 is a single position in the genome, in or near the near VSX2 gene. Published research associates it with refractive error. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35797567 linked to?

On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.

Does having rs35797567 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35797567 come from?

GWAS Catalog, Nature genetics 2026, PMID:42009823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Refractive error (rs35797567). MyGeneLog™. https://www.mygenelog.com/variants/rs35797567

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