Vertical cup-disc ratio (adjusted for vertical disc diameter)
FENDRR · rs35526343
0 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 67,040 British ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.02 lower (95% confidence interval 0.016-0.024); p = 9 × 10−13.
How common The C allele had a frequency of about 96% in the people studied.
Where it sits Chromosome 16, band 16q24.1 — between genes, 42.8 kb from FENDRR.
What each result means
C/CTwo copies of the version the research linked to Vertical cup-disc ratio (adjusted for vertical disc diameter). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Vertical cup-disc ratio (adjusted for vertical disc diameter). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Vertical cup-disc ratio (adjusted for vertical disc diameter). This is the starting point the study compared everyone against.
rs35526343 is a single position in the genome, in or near the FENDRR gene. Published research associates it with vertical cup-disc ratio (adjusted for vertical disc diameter). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs35526343 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs35526343 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35526343 come from?
GWAS Catalog, Nature genetics 2020, PMID:31959993. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Vertical cup-disc ratio (adjusted for vertical disc diameter) (rs35526343). MyGeneLog™. https://www.mygenelog.com/variants/rs35526343