Sensitive

Type 1 diabetes (age at diagnosis)

HLA-DQA2 · rs35122968

Where this position leads

Condition: Type 1 Diabetes

rs35122968 Condition: Type 1 Diabetes Type 1 Diabetes Condition rs35122968 rs35122968 HLA-DQA2

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Type 1 diabetes (age at diagnosis) compared to the general population. (GWAS Catalog, J Intern Med 2020, PMID:33179336)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Type 1 diabetes (age at diagnosis). (GWAS Catalog, J Intern Med 2020, PMID:33179336)
T/T Published research associates this genotype with typical/baseline likelihood of Type 1 diabetes (age at diagnosis) — no copies of the reported risk allele. (GWAS Catalog, J Intern Med 2020, PMID:33179336)

Source: GWAS Catalog, J Intern Med 2020, PMID:33179336

Questions about rs35122968

What is rs35122968?

rs35122968 is a single position in the genome, in or near the HLA-DQA2 gene. Published research associates it with type 1 diabetes (age at diagnosis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35122968 linked to?

On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs35122968 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35122968 come from?

GWAS Catalog, J Intern Med 2020, PMID:33179336. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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