CETP · rs34620476
Where this position leads
Drug: Statins
What the study found
Who was studied 115,006 European ancestry individuals.
The effect Each copy of the C allele shifted the measure 0.0307 lower (95% confidence interval 0.023-0.039); p = 2 × 10−14.
How common The C allele had a frequency of about 57% in the people studied.
Where it sits Chromosome 16, band 16q13 — in an intron of CETP.
What ClinVar records
Classification
Benign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2018-08-30.
ClinVar record 1257695 NM_000078.3(CETP):c.119-273C>A
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
rs34620476 is a single position in the genome, in or near the CETP gene. Published research associates it with ratio of linoleic acid to total fatty acids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
CETP carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Ratio of linoleic acid to total fatty acids (rs34620476). MyGeneLog™. https://www.mygenelog.com/variants/rs34620476