0 21142338Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others8Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 12,719 African American or Afro-Caribbean cases, 102,556 African American or Afro-Caribbean controls, 5,082 Hispanic or Latin American cases, 51,953 Hispanic or Latin American controls, 370 East Asian ancestry cases, 6,267 East Asian ancestry controls, 43,559 European ancestry cases, 384,389 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.0846 lower (95% confidence interval 0.067-0.102); p = 4 × 10−18.
How common The C allele had a frequency of about 86% in the people studied.
Where it sits Chromosome 12, band 12p12.1 — in an intron of SOX5.
What each result means
C/CTwo copies of the version the research linked to Spinal stenosis (PheCode 720). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Spinal stenosis (PheCode 720). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Spinal stenosis (PheCode 720). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs34616559
What is rs34616559?
rs34616559 is a single position in the genome, in or near the SOX5 gene. Published research associates it with spinal stenosis (phecode 720). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs34616559 linked to?
On MyGeneLog this position is linked to Spinal Stenosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs34616559 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34616559 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 21142338Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others8Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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