LMX1B · rs34186918
Where this position leads
Condition: Glaucoma
What the study found
Who was studied 5,215 European ancestry cases, 95,653 European ancestry controls.
The effect Each copy of the T allele shifted the measure 0.164 higher (95% confidence interval 0.12-0.21); p = 3 × 10−12.
How common The T allele had a frequency of about 24% in the people studied.
Where it sits Chromosome 9, band 9q33.3 — in an intron of LMX1B.
rs34186918 is a single position in the genome, in or near the LMX1B gene. Published research associates it with medication use (antiglaucoma preparations and miotics). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Medication use (antiglaucoma preparations and miotics) (rs34186918). MyGeneLog™. https://www.mygenelog.com/variants/rs34186918