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Who was studied 203 European ancestry cases, 398 European ancestry controls.
The effect
Each copy of the A allele carried 2.18 times the odds of Ophthalmic complications in type 2 diabetes (95% confidence interval 1.66-2.87); p = 3 × 10−8.
How common The A allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 7, band 7q11.23 — in an intron of DTX2P1-UPK3BP1-PMS2P11.
What each result means
A/ATwo copies of the version the research linked to Ophthalmic complications in type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Ophthalmic complications in type 2 diabetes. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Ophthalmic complications in type 2 diabetes. This is the starting point the study compared everyone against.
BMC medical genomics · 2021 · PMID 33430853 · open access
Questions about rs3095447
What is rs3095447?
rs3095447 is a single position in the genome, in or near the CCDC146 gene. Published research associates it with ophthalmic complications in type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3095447 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs3095447 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3095447 come from?
GWAS Catalog, BMC medical genomics 2021, PMID:33430853. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Ophthalmic complications in type 2 diabetes (rs3095447). MyGeneLog™. https://www.mygenelog.com/variants/rs3095447