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Who was studied 11,964 Japanese ancestry cases, 240,675 Japanese ancestry controls, 5,153 European ancestry cases, 626,533 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.0948 higher (95% confidence interval 0.064-0.126); p = 1 × 10−9.
How common The G allele had a frequency of about 54% in the people studied.
Where it sits Chromosome 11, band 11q13.3 — in an intron of TPCN2.
What each result means
A/ANo copy of the version the research linked to Duodenal ulcer. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Duodenal ulcer. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Duodenal ulcer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2023 · PMID 38036781 · open access
Questions about rs3019776
What is rs3019776?
rs3019776 is a single position in the genome, in or near the TPCN2 gene. Published research associates it with duodenal ulcer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3019776 linked to?
On MyGeneLog this position is linked to Duodenal Ulcer. The research behind each link, and its sources, are set out on that condition page.
Does having rs3019776 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3019776 come from?
GWAS Catalog, Nature genetics 2023, PMID:38036781. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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