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Hematological and biochemical traits

PARVB · rs2896019

Where this position leads

Condition: Blood Cell Counts

rs2896019 Condition: Blood Cell Counts Blood Cell Counts Condition Topic: Infection and immunity Infection and immunity Topic rs2896019 rs2896019 PARVB

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied Up to 14,402 Japanese individuals.

The effect Each copy of the G allele shifted the measure 0.085 lower (95% confidence interval 0.061-0.109); p = 2 × 10−12.

How common The G allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 22, band 22q13.31 — in an intron of PNPLA3.

What each result means

G/G Two copies of the version the research linked to Hematological and biochemical traits. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Hematological and biochemical traits. That is a smaller link than two copies.
T/T No copy of the version the research linked to Hematological and biochemical traits. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2896019

What is rs2896019?

rs2896019 is a single position in the genome, in or near the PARVB gene. Published research associates it with hematological and biochemical traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2896019 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs2896019?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (4 papers), blood sugar and insulin (2 papers), liver (2 papers), alcohol and the flush (1 papers), bones and fractures (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2896019 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2896019 come from?

GWAS Catalog, Nat Genet 2010, PMID:20139978. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hematological and biochemical traits (rs2896019). MyGeneLog™. https://www.mygenelog.com/variants/rs2896019

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