A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index and type 2 diabetes (pairwise) compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index and type 2 diabetes (pairwise).
G/GPublished research associates this genotype with typical/baseline likelihood of Body mass index and type 2 diabetes (pairwise) — no copies of the reported risk allele.
rs2881654 is a single position in the genome, in or near the PPARG gene. Published research associates it with body mass index and type 2 diabetes (pairwise). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2881654 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs2881654 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2881654 come from?
GWAS Catalog, Nat Metab 2021, PMID:33619380. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.