C4orf36 · rs28641910
Where this position leads
Condition: Age-Related Macular Degeneration
What the study found
Who was studied 98,316 European ancestry individuals.
The effect Each copy of the G allele shifted the measure 0.0698 higher (95% confidence interval 0.045-0.094); p = 9 × 10−9.
How common The G allele had a frequency of about 37% in the people studied.
Where it sits Chromosome 4, band 4q21.3 — in an intron of C4orf36.
rs28641910 is a single position in the genome, in or near the C4orf36 gene. Published research associates it with phospholipids to total lipids in large vldl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Phospholipids to Total Lipids in Large VLDL percentage (rs28641910). MyGeneLog™. https://www.mygenelog.com/variants/rs28641910