Sensitive

Substance use disorder

SZT2 · rs2842179

Where this position leads

Condition: Substance Use Disorder

rs2842179 Condition: Substance Use Disorder Substance Use Disorder Condition rs2842179 rs2842179 SZT2

What the study found

Who was studied 1,458,999 European ancestry individuals, 240,296 African ancestry individuals, 58,370 mixed American ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 6 × 10−9.

Where it sits Chromosome 1, band 1p34.2 — in an intron of SZT2.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Substance use disorder — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Substance use disorder.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Substance use disorder compared to the general population.
Source

Questions about rs2842179

What is rs2842179?

rs2842179 is a single position in the genome, in or near the SZT2 gene. Published research associates it with substance use disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2842179 linked to?

On MyGeneLog this position is linked to Substance Use Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs2842179 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2842179 come from?

GWAS Catalog, Molecular psychiatry 2026, PMID:41057643. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Substance use disorder (rs2842179). MyGeneLog™. https://www.mygenelog.com/variants/rs2842179

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